CBDA: Health Benefits You Need To Know

Health Benefits of CBDA

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CBDA (cannabidiolic acid) is a relatively unknown cannabinoid with significant medicinal potential. There are many health benefits you need to know about CBDA. CBDA has been demonstrated to alleviate inflammation, anxiety, seizures, and possibly certain types of cancer in preclinical tests. CBDA is already being hailed as the next big thing in cannabinoid medicine.

While research on CBDA’s potential advantages is still in its early stages, experts are optimistic that it will lessen the need for pharmaceuticals with long-term adverse effects while also enhancing people’s general mental and physical well-being. We shall understand what CBDA is and what health benefits it provides in this article. So let’s get this party started!

What exactly is CBDA?

Since Israeli scientist Rafael Mechoulam discovered CBDA in 1965, it has piqued the interest of researchers.

So, what exactly is CBDA? The natural precursor to the cannabidiol (CBD) molecule is cannabidiolic acid (CBDA). CBDA is converted to CBD, the active ingredient in many infused products when the acidic form is decarboxylated.

When cannabis is heated, it undergoes the decarboxylation process. Cannabinoids change their molecular structure when heated, dried, or processed. The method eliminates one acidic carboxyl group from the molecular chain in terms of chemical makeup.

According to new research, activating the cannabinoid acid isn’t entirely required to obtain its medical advantages. CBDA has been demonstrated to be more effective than CBD in treating certain disorders in some situations.

Also Read: How To Use CBD Salve For Headache

CBDA vs. CBD: Does CBDA Get You High?

Intoxication is not caused by CBDA or CBD. THC and CBD, for example, bind to the CB1 and CB2 cannabinoid receptors, whereas other acidic cannabinoids take a different approach.

CBDA affects the endocannabinoid system by blocking the Cox-2 enzyme, but it does not affect the central nervous system.

CBDA may be utilized as a treatment for a range of medical ailments. Patients who do not wish to feel impaired can use CBDA.  It is more effective than CBD to treat ailments.

Health Benefits of CBDA

CBDA has shown to be a promising therapy for the treatment of a range of ailments. CBDA’s affinity for serotonin receptors allows it to influence mood, nausea, and inflammation.

CBDA : CBGA Full Spectrum Tincture
CBDA: CBGA Full Spectrum Tincture

CBDA has been demonstrated to activate 5-HT1A serotonin receptors more strongly than CBD. CBDA’s potential as a treatment is still up in the air, according to current research.

Clinical experiments have mostly relied on animal models up until now. We won’t know the full scope of CBDA’s power until trials focus on human health and how CBDA operates. Here are a few of CBDA’s promising advantages:


Epidiolex is CBD-based and became the first FDA-approved cannabis-derived prescription drug product for treatment-resistant epilepsy. As a result, its acidic precursor may help to lessen the intensity and frequency of seizures.

The pharmaceutical company behind Epidiolex, GW Pharma, has conducted tests comparing the effects of CBDA and CBD. CBDA has been reported to have greater bioavailability and a faster-acting impact than its parent molecule in various tests.

In essence, their research found that lower CBDA doses were necessary to be successful, reducing the chance of harmful CBDA side effects. CBDA was found to be more beneficial than CBD in decreasing seizures in some cases.

Also Read: How To Make Hemp Butter For Skin


CBDA has anti-inflammatory properties and may be able to reduce inflammation due to its selective Cox-2 inhibitor properties. The functions of cyclooxygenase (Cox) enzymes 1 and 2 are distinct.

CBD Full Spectrum Softgels
CBD Full Spectrum Softgels

Cox-1 is in charge of keeping the stomach and intestinal lining in good shape. Inflammation is caused by Cox-2. Ibuprofen and aspirin are examples of nonsteroidal anti-inflammatory medicines (NSAIDs) that operate by blocking the effects of these enzymes. Long-term usage of these medicines can harm the gastrointestinal tract.

As a result, scientists have been concentrating their efforts on developing selective Cox-2 inhibitors that avoid blocking Cox-1 enzymes without causing significant damage to the stomach and intestinal mucosa. CBDA operates in the same way that NSAIDs do, but without gastrointestinal side effects.


Researchers from Guelph University in Ontario evaluated the effects of CBD against CBDA on various types of vomiting and nausea. CBDA was discovered to be an effective treatment for nausea and vomiting caused by a toxin or motion-induced vomiting and nausea.

CBDA was found to be particularly effective at reducing anticipatory nausea in the study. This happens when a person becomes sick just before starting chemotherapy. CBDA is a very promising avenue because there are no known therapies for this type of nausea.

The researchers also evaluated the effects of CBDA and ondansetron, an anti-nausea medicine, in a second study. The researchers discovered that even a very modest dose of CBDA boosts the antiemetic efficacy of the medicine. A 1000-fold lower dose of CBDA provides the same effect as CBD.


CBDA was discovered to help restrict the spread of a specific type of breast cancer cell in a preclinical investigation concentrating on the downregulation of Cox-2 enzymes. The concentration of Cox-2 in this form of cancer is higher than average.

CBDA was used for 48 hours during the research, lowering the efficiency of the Id-1 protein.  This protein is linked to cancer cell proliferation and survival, it also reduced the effectiveness of Cox-2. Furthermore, CBDA appears to boost Sharp-1 expression, been linked to the prevention of breast cancer metastasis.

While further research into CBDA’s cancer-fighting abilities is needed, it is showing significant promise in its ability to decrease dangerous cells in the body.

How to use CBDA?

Consumers can obtain a variety of CBDA-rich goods, including CBD extract, in today’s fast-growing CBD industry. Whole-plant, full-spectrum products include the entire chemical profile of the plant, including major and minor cannabinoids, terpenes, and other bioactive components. CBDA cannot be smoked in its natural state because the cannabinoid acid is converted to CBD.

Also Read: Does CBD Work For High Blood Pressure

Final Words

Cannabis flowers and leaves are used as a culinary component in their natural state. It’s possible to get your greens without getting high by eating the leaves raw in a salad, adding them to a smoothie, or making raw cannabis juice.

HempDepotCo is what you need for all your CBD needs. Check out CBD Gummies and CBD Tinctures on their website and kickstart your CBD journey!

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